A Prognostic Molecular Signature of Hepatic Steatosis is Spatially Heterogeneous and Dynamic in Human Liver

Medicine, Hepatobiliary System, Endocrinology, Gastroenterology,
hepatic steatosis   molecular signature   spatial heterogeneity   dynamic   liver   metabolic disease   biomarkers  

Academic Background Metabolic-associated Steatotic Liver Disease (MASLD) is a major health issue affecting over 30% of the global population and is closely related to various chronic diseases such as cancer, cardiovascular disease, and renal dysfunction. The pathological spectrum of MASLD ranges from simple steatosis to steatohepatitis and progress...

Amino Acid is a Major Carbon Source for Hepatic Lipogenesis

Medicine, Hepatobiliary System, Gastroenterology, Life Sciences, Biochemistry,
liver   lipogenesis   amino acids   metabolic dysfunction   nutrient intake   low-protein diet   obesity  

Research Report on the Relationship Between High Protein Diet and Liver Fat Synthesis Background and Significance Globally, the prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is gradually increasing, becoming a common issue among people with obesity and insulin resistance. The pathological development of this disease...