Obesity is a growing global health issue, closely linked to metabolic diseases such as cardiovascular diseases and diabetes, as well as lymphatic dysfunction. The lymphatic system plays a crucial role in maintaining fluid balance, immune responses, and fat metabolism. However, lymphatic function is often impaired in obese patients, leading to compl...
In modern society, sleep deficiency has become one of the major causes of metabolic diseases. Studies have shown that insufficient sleep increases energy intake, but its effects on energy expenditure remain unclear. Although some clinical research indicates that sleep-deprived populations exhibit greater energy intake, energy expenditure does not c...
Research Report on the Relationship Between High Protein Diet and Liver Fat Synthesis Background and Significance Globally, the prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is gradually increasing, becoming a common issue among people with obesity and insulin resistance. The pathological development of this disease...
Obesity Aggravates Female Central Nervous System Autoimmune Diseases Through Sex-Specific Interferon Signaling In recent years, the rising incidence of central nervous system (CNS) autoimmune diseases in females has garnered widespread attention. Obesity, as a potential environmental risk factor, has gradually become a research hotspot. The latest ...
Background and Research Motivation Obesity has been identified as an important risk factor for various malignancies. It not only promotes the growth and spread of tumor cells but also leads to generally poorer prognosis in patients. However, recent research has found that obese patients receiving immune checkpoint inhibitors (ICI) therapy, especial...
Reactivation of Insulin Receptors Can Restore Brain Function in Early Lepr-Deficient Mice Background Obesity is a chronic disease caused by excessive fat accumulation, affecting both body and brain health. Deficiency of the insulin receptor (Leptin receptor, Lepr) is considered an important factor in the pathogenesis of obesity. Insulin plays a cru...
Obesity Disrupts Pituitary-Hepatic UPR Communication Leading to NAFLD Progression Background and Research Objectives In recent years, the incidence of non-alcoholic fatty liver disease (NAFLD) has increased significantly. Research suggests that obesity, a major risk factor for NAFLD, disrupts hepatic immunometabolic homeostasis by affecting systemi...
Study on the Association# Study on the Association Between Body Composition Patterns, Cardiovascular Diseases Between, Body and Neurodegenerative Composition Disease Risks Background Neurodegenerative Patterns diseases, including Alzheimer’s Disease (AD) and Parkinson’s Disease, (PD), currently affect over Cardiovascular Diseases, and Neuro60degene...
Research on Saturated Fatty Acids and Brain Function Background Introduction Obesity and metabolic syndrome are major global health challenges today. Numerous studies have shown that excessive consumption of diets rich in saturated fats leads to obesity, accompanied by a series of metabolic complications such as insulin resistance and diabetes. How...
Research Review on Aging-Exacerbated Metabolic Dysfunction-Related Lipid Liver Diseases Academic Background As the aging population increases, metabolic diseases induced by aging are becoming a severe public health challenge. The liver, being the primary metabolic organ, requires special attention to its functional disorders during aging. Studies h...