Genome-Wide Loss of Heterozygosity Predicts Aggressive, Treatment-Refractory Behavior in Pituitary Neuroendocrine Tumors

Medicine, Endocrinology, Neurology, Oncology, Life Sciences, Cell Biology, Biochemistry, Genetics,
aggressive pituitary tumor   treatment-refractory pituitary tumor   pituitary carcinoma   pituitary neuroendocrine tumor   loss of heterozygosity   biomarker  

Prediction of Invasiveness and Treatment Resistance Behavior of Pituitary Neuroendocrine Tumors Based on Genome-Wide Loss of Heterozygosity Background: Pituitary neuroendocrine tumors (PitNETs) are mostly benign, but a small portion exhibit invasive and treatment-resistant behaviors, continuing to grow or metastasize even after surgery, conventiona...