Nucleobase Adducts Bind MR1 and Stimulate MR1-Restricted T Cells

Medicine, Rheumatology and Immunology, Medical Laboratory Science, Gastroenterology, Oncology, Life Sciences, Cell Biology, Immunology,
nucleobase adducts   mr1   t cells   tumor cells   carbonyl stress   metabolic changes   antigens  

Nucleotide Base Adducts Bind MR1 and Stimulate MR1-Restricted T Cells Abstract This article provides an overview of the latest research by Vacchini et al. on MR1-restricted T cells (MR1T cells), which discovered the presence of nucleotide base adducts as MR1T cell antigens and unveiled their metabolic pathways and physiological functions in tumor c...