Neocortical Somatostatin Neuron Diversity in Cognition and Learning

Medicine, Neurology,
neocortex   somatostatin neurons   cognition   learning   neuronal diversity   plasticity   cortical function  

Academic Background In the mammalian neocortex, somatostatin (SST)-expressing neurons are a major class of inhibitory interneurons that exhibit diversity in electrophysiology and morphology, and are involved in various cognitive functions such as learning, memory, and sensory processing. However, despite extensive research on the diversity of SST n...

Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening

Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening

Medicine, Rheumatology and Immunology, Nephrology, Gastroenterology, Life Sciences, Immunology,
T cells   plasticity   kidney inflammation   gut inflammation   single-cell CRISPR   autoimmune diseases  

Targeting T Cell Plasticity to Treat Inflammation in the Kidney and Gut: A Study Using Pooled Single-cell CRISPR Screening Background of the Study This paper, co-authored by Leon U.B. Enk and others, was published in the June 14, 2024, issue of “Science Immunology” under the title “Targeting T cell plasticity in kidney and gut inflammation by poole...