Academic Background G protein-coupled receptors (GPCRs) are the most abundant family of cell surface receptors in the human body and are also the most common targets of FDA-approved drugs. GPCRs play a crucial role in the treatment of various diseases, including pain, diabetes, cardiovascular diseases, and cancer. However, drug development targetin...

Modulation of Electrical Synapses and Excitability by Dopamine Receptors in the Thalamic Reticular Nucleus Academic Background The Thalamic Reticular Nucleus (TRN) is a thin shell of γ-aminobutyric acid (GABA)ergic inhibitory neurons in the thalamus. These neurons are coupled via gap junctions and regulate the transmission of sensory information fr...