Intensity-Dependent Effects of TDCS on Motor Learning Are Related to Dopamine

The Intensity-Dependent Effects of Cortical Electrical Stimulation on Motor Learning and the Role of Dopamine Background Introduction Nowadays, non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) are widely used in neuroplasticity research to modulate cognition and behavior. However, optimizing stimulati...

YEATS2 Knockdown Impairs Dopaminergic Synaptic Integrity and Leads to Seizure-like Behaviors in Drosophila Melanogaster

A Study on the Effect of YEATS2 Gene Knockdown on Dopaminergic Synaptic Integrity and Epileptic-like Behavior in Drosophila Background Introduction Epilepsy is a common neurological disorder characterized by abnormal electrical activities in the brain. These abnormal activities can lead to seizures and other neurological symptoms. Familial adult my...

Dopamine and Serotonin in Human Substantia Nigra Track Social Context and Value Signals During Economic Exchange

Dopamine and Serotonin in Human Substantia Nigra Track Social Context and Value Signals During Economic Exchange

Background Introduction In contemporary neuroscience research, dopamine and serotonin are hypothesized to be crucial neuromodulators guiding social behavior. However, there is a significant lack of understanding regarding the dynamic changes of these neuromodulators during social interactions. Although non-invasive functional neuroimaging methods (...

Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency

This paper reports a study on the cognitive representation of intracranial self-stimulation (ICSS) of midbrain dopamine neurons. The authors aimed to answer why rats work to obtain ICSS, i.e., how the pulsatile activation of dopamine neurons is represented in the brain. Research Background: The pulsatile activation of dopamine neurons is typically ...