IDH Mutation, Glioma Immunogenicity, and Therapeutic Challenge of Primary Mismatch Repair Deficient IDH-Mutant Astrocytoma (PMMRDIA): A Systematic Review

Medicine, Neurosurgery, Oncology, Life Sciences, Immunology,
IDH mutation   glioma   immunogenicity   mismatch repair deficiency   astrocytoma   therapeutic challenge   systematic review  

Immunogenicity and Therapeutic Challenges of IDH-Mutant Gliomas Background Glioma is a common central nervous system tumor, and its treatment and prognosis vary significantly depending on molecular characteristics. In recent years, the diagnostic and prognostic significance of isocitrate dehydrogenase (IDH) mutations in gliomas has been increasingl...

Mortality Risk Prediction Models for People with Kidney Failure: A Systematic Review

Medicine, Nephrology,
kidney failure   mortality risk   prediction models   systematic review   clinical applicability   risk of bias   treatment decisions  

Systematic Review of Mortality Risk Prediction Models for Patients with Kidney Failure Academic Background Kidney failure is a severe chronic condition, with a significant decline in both quality of life and survival rates compared to patients with other chronic diseases, including some forms of non-metastatic cancer. Patients with kidney failure o...