Epigenome-Wide Association Studies Identify Novel DNA Methylation Sites Associated with PTSD: A Meta-Analysis of 23 Military and Civilian Cohorts

Medicine, Psychiatry, Life Sciences, Biochemistry, Genetics,
PTSD   DNA methylation   post-traumatic stress disorder   epigenetics   gene expression   meta-analysis   genome-wide association studies  

Epigenome-wide DNA Methylation Study Highlights PTSD-Associated Sites: A Meta-Analysis Across 23 Military and Civilian Cohorts Background and Research Objectives Post-Traumatic Stress Disorder (PTSD) is a serious psychiatric condition triggered by exposure to traumatic events. It is characterized by intrusive memories, avoidance or emotional numbne...

Comparative Efficacy of Balanced Crystalloids versus 0.9% Saline on Delayed Graft Function and Perioperative Outcomes in Kidney Transplantation: A Meta-Analysis of Randomised Controlled Trials

Medicine, Anesthesiology, Nephrology,
balanced crystalloid   0.9% saline   delayed graft function   kidney transplantation   perioperative outcomes   meta-analysis   randomised controlled trials  

Comparative Efficacy of Balanced Crystalloids versus 0.9% Saline on Delayed Graft Function and Perioperative Outcomes in Kidney Transplantation: A Meta-Analysis of Randomised Controlled Trials Academic Background Kidney transplantation is an effective treatment for end-stage renal disease (ESRD), but delayed graft function (DGF) post-transplantatio...

Glutamatergic Medications for Obsessive-Compulsive and Related Disorders: A Systematic Review and Meta-Analysis

Medicine, Psychiatry,
glutamatergic medications   obsessive-compulsive disorder   meta-analysis   randomized controlled trials   neuropsychiatric disorders   treatment efficacy   subgroup analysis  

A Systematic Review and Meta-Analysis of Glutamatergic Medications for Obsessive-Compulsive and Related Disorders (OCRDs) Academic Context Obsessive-Compulsive and Related Disorders (OCRDs) represent a group of neuropsychiatric conditions characterized by excessive, persistent obsessions or compulsions. These disorders include Obsessive-Compulsive ...

Diagnostic Accuracy of CT for the Detection of Hepatic Steatosis: A Systematic Review and Meta-Analysis

Medicine, Hepatobiliary System, Gastroenterology, Medical Imaging,
hepatic steatosis   CT diagnosis   meta-analysis   noncontrast CT   contrast-enhanced CT   dual-energy CT   diagnostic accuracy  

Diagnostic Accuracy of CT for the Detection of Hepatic Steatosis: A Systematic Review and Meta-Analysis Academic Background Hepatic steatosis is the result of the abnormal accumulation of triglycerides in hepatocytes, which can initiate a cascade of inflammatory responses, referred to as steatotic liver disease (SLD). Metabolic dysfunction–associat...

Convergent Neuroimaging and Molecular Signatures in Mild Cognitive Impairment and Alzheimer's Disease: A Data-Driven Meta-Analysis with n = 3,118

Convergent Neuroimaging and Molecular Signatures in Mild Cognitive Impairment and Alzheimer's Disease: A Data-Driven Meta-Analysis with n = 3,118

Medicine, Neurology, Medical Imaging,
Alzheimer's disease   structural magnetic resonance imaging   meta-analysis   brain atrophy   gene set enrichment analysis  

Neuroimaging and Molecular Markers in Alzheimer’s Disease: Data-Driven Meta-Analysis Research Background Alzheimer’s Disease (AD) is a chronic neurodegenerative disease characterized mainly by progressive memory loss and cognitive impairment, making it the most common type of dementia. Neuronal loss, one of the primary hallmarks of AD, is closely a...