Nickel-Mediated Aerobic C(sp2)–Nucleophile Coupling Reactions for Late-Stage Diversification of Aryl Electrophiles

Chemistry, Organic Chemistry, Medicinal Chemistry, Catalysis,
Nickel catalysis   C(sp2)–nucleophile coupling   Aryl electrophiles   Late-stage diversification   Oxidation reactions  

In the field of medicinal chemistry, molecular diversification is a crucial step in the discovery of new drugs. However, existing catalytic methods often face challenges when dealing with complex drug molecules, as these molecules are typically more complex than simple substrates. In particular, the formation of carbon-heteroatom (C–X) bonds is an ...

A Pickering-Emulsion-Droplet-Integrated Electrode for the Continuous-Flow Electrosynthesis of Oximes

Chemistry, Energy Chemistry, Physical Chemistry, Materials Chemistry, Catalysis, Chemical Engineering,
Pickering emulsion   electrosynthesis   oximes   continuous flow   electrocatalysis   interfacial reaction   industrial application  

Cyclohexanone oxime is a critical intermediate in the production of nylon-6, with global nylon-6 production projected to reach 8.9 million tons by 2024, leading to an increasing demand for cyclohexanone oxime. Traditional methods for synthesizing cyclohexanone oxime primarily involve the reaction of hydroxylamine (NH2OH) with cyclohexanone. However...

Synthesis and Reactivity of an Antimony(III) Dication

Synthesis and Reactivity of an Antimony(III) Dication

Chemistry, Inorganic Chemistry, Catalysis,
antimony dication   Lewis acid   density functional theory   hydroamination   main-group compounds  

In enzyme catalysis, the proximity effect is a common phenomenon that forces reactions to occur by bringing two or more molecules close together. To achieve this effect, the active center requires multiple binding sites to preorganize reactants before the reaction. Although this effect has been extensively studied in enzyme catalysis, its applicati...

Late-Stage Deuteration and Tritiation through Bioinspired Cooperative Hydrogenolysis

Chemistry, Organic Chemistry, Medicinal Chemistry, Catalysis,
hydrogenolysis   deuteration   tritiation   bioinspired   homogeneous catalysis  

Academic Background Hydrogenolysis, a fundamental chemical reaction that breaks chemical bonds through the addition of molecular hydrogen, is widely used in the upgrading of biomass, petroleum, and other feedstocks into high-value chemicals and fuels. Additionally, hydrogenolysis plays a crucial role in the pharmaceutical and fine chemical industri...

Atomic-Scale Insights into Topotactic Transformations in an Extra-Large-Pore Zeolite Using Time-Resolved 3D Electron Diffraction

Chemistry, Nanoscience, Catalysis, Chemical Engineering, Materials Science, Inorganic Non-Metallic Materials,
zeolite   topotactic transformation   time-resolved electron diffraction   extra-large-pore structure   atomic scale   materials engineering   solid-state reactions  

Academic Background Zeolites are microporous materials with regular channel structures, widely used in catalysis, adsorption, and ion exchange. Due to their unique pore structures and chemical properties, zeolites hold significant application value in petrochemicals, environmental protection, and energy storage. However, the synthesis and structura...

A Portable Device Utilizing High-Entropy Perovskite Aerogels for Efficient Energy Conversion from Atmospheric Water

Chemistry, Energy Chemistry, Materials Chemistry, Catalysis, Engineering, Environmental Engineering, Energy Engineering, Materials Science, Inorganic Non-Metallic Materials,
high-entropy perovskite   aerogel   solar evaporation   water harvesting   oxygen evolution reaction  

Academic Background The global scarcity of water and energy resources is particularly severe in arid and remote regions, and this issue has become even more urgent in the context of intensifying climate change. Traditional methods of water and energy acquisition, such as seawater desalination or large-scale power transmission, are not only costly a...

Optimizing Oxygen Reduction Reaction through Enhanced Mesoscopic Mass Transport in Ordered Mesoporous Carbon Nanofibers

Chemistry, Energy Chemistry, Materials Chemistry, Catalysis, Engineering, Energy Engineering, Materials Science, Inorganic Non-Metallic Materials,
oxygen reduction reaction   mass transfer   carbon nanofiber   mesoporosity   electrocatalysis   zinc-air battery   non-precious metal catalysts  

Academic Background As the global demand for green energy continues to grow, fuel cells and metal-air batteries are considered potential solutions for energy conversion and storage due to their high energy density. However, the commercialization of these technologies is hindered by the slow kinetics of the oxygen reduction reaction (ORR) at the cat...

Dual-functional Cu2O/g-C3N4 Heterojunctions: A High-performance SERS Sensor and Photocatalytic Self-cleaning System for Water Pollution Detection and Remediation

Chemistry, Analytical Chemistry, Materials Chemistry, Catalysis, Environmental Chemistry, Engineering, Environmental Engineering, Materials Science, Inorganic Non-Metallic Materials,
Cu2O/g-C3N4   SERS sensor   photocatalysis   water pollution detection   self-cleaning system   heterojunction   environmental remediation  

Dual-Functional Cu₂O/g-C₃N₄ Heterojunctions: A High-Performance SERS Sensor and Photocatalytic Self-Cleaning System for Water Pollution Detection and Remediation Academic Background With the rapid expansion of industrialization and agricultural activities, water pollution has become a significant global environmental issue. Large quantities of harm...

High-yield Porphyrin Production Through Metabolic Engineering and Biocatalysis

High-yield Porphyrin Production Through Metabolic Engineering and Biocatalysis

Chemistry, Organic Chemistry, Catalysis, Chemical Engineering, Life Sciences, Biochemistry, Bioengineering,
metabolic engineering   biocatalysis   porphyrin   heme   zincphyrin   bacteria   fermentation  

This study was published in the journal Nature Biotechnology, with the doi 10.1038/s41587-024-02267-3. The corresponding authors are Haihong Chen and Yaohong Wang from East China University of Science and Technology, and the publication date is April 26, 2024. The article investigates the high-yield production of chlorophyll through metabolic engin...