Retention of UC-II® Undenatured Type II Collagen During Functional Food and Beverage Prototype Processing

UC-II® Undenatured Type II Collagen Retention in Functional Food and Beverage Processing Academic Background Collagen is widely used in the food and beverage industry to enhance the nutritional and health value of products. Specifically, undenatured type II collagen (UC-II®) has garnered attention for its potential benefits to joint health. However...

High Performance of Functionalized Carbon Dots in the Detection of Dye Contaminants

High-Performance SERS Detection of Dye Contaminants Using Novel Functionalized Carbon Dots Academic Background Dye molecules play a vital role in daily life, but the environmental pollution caused by their use cannot be ignored. Among them, Malachite Green (MG) is a triphenylmethane dye with potential carcinogenic, teratogenic, and mutagenic effect...

Metal-Free Production of Natural Blue Colorants through Anthocyanin-Protein Interactions

Metal-Free Production of Natural Blue Colorants: Novel Insights from Anthocyanin-Protein Interactions Academic Background With increasing consumer awareness of health and natural food ingredients, the demand for natural colorants has been on the rise. However, natural blue colorants are scarce, and their production poses significant challenges. Cur...

Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy

Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy

Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy Academic Background In environmental and safety monitoring, real-time, highly selective, and highly sensitive detection of trace gaseous compounds is a significant challenge. Particularly for emerging environmental pollutants such as per- and polyfluoro...

A Spectroscopic Method for Distinguishing Two Novel Sandwich-Type Tungsten Oxide Cluster Compounds

Distinguishing Novel Sandwich-Type Tungsten Oxide Cluster Compounds Using Two-Dimensional Correlation Infrared Spectroscopy Background Introduction Polyoxometalates (POMs) are metal-oxygen cluster compounds linked through oxygen coordination with transition metal ions. They play significant roles in catalysis, optics, medicine, and magnetism. Howev...

Ion-Concentration-Dependent Dynamic Mechanism of Thiolactic-Acid-Capped Gold Nanoclusters Revealed by Fluorescence Spectra and Two-Dimensional Correlation Spectroscopy

Background and Research Questions Atomic gold nanoclusters (AuNCs), with particle sizes typically not exceeding 2 nanometers, have garnered extensive attention in recent years due to their unique photophysical properties, making them highly advantageous in biomedicine, catalysis, and sensing. These properties include excellent catalytic activity, t...

Fully Automated Sample-to-Result Simple-RPA Microfluidic Chip for In Ovo Sexing Application

Fully Automated Microfluidic Chip-Based Embryo Sexing Technology Academic Background In the egg-laying poultry industry, newly hatched male chicks are often culled immediately after hatching, as they neither lay eggs nor produce high-quality meat. Each year, approximately 372 million male chicks are culled in the European Union. This practice has s...

The Development and Application of an Engineered Direct Electron Transfer Enzyme for Continuous Levodopa Monitoring

Development of an Engineered Direct Electron Transfer Enzyme for Continuous Levodopa Monitoring Background Parkinson’s Disease (PD) is a chronic neurodegenerative disease that affects millions of people worldwide. It is characterized by the loss of dopaminergic neurons in the substantia nigra and the presence of α-synuclein aggregations forming Lew...

Isolation and Identification of Three New Isomer Impurities in Milbemycin Oxime Drug Substance

Isolation and Identification of Three New Isomer Impurities in Milbemycin Oxime Drug Substance Academic Background Milbemycins are a class of 16-membered macrolides produced by Streptomyces, exhibiting potent anthelmintic and insecticidal activities with low mammalian toxicity. Milbemycins and their derivatives are widely used in agriculture and ve...

Nonemissive Iridium(III) Solvent Complex as a Self-Reporting Photosensitizer for Monitoring Phototherapeutic Efficacy in a 'Signal On' Mode

Iridium(III) Solvent Complex as a Self-Reporting Photosensitizer for Monitoring Phototherapeutic Efficacy Academic Background Cancer is one of the leading causes of global mortality, significantly impacting patients’ quality of life. In recent years, photodynamic therapy (PDT) has garnered considerable attention as a promising technology for cancer...