Adeno-Associated Virus-Mediated Trastuzumab Delivery to the Central Nervous System for Human Epidermal Growth Factor Receptor 2+ Brain Metastasis

AAV-Mediated Trastuzumab Delivery to the Central Nervous System for EGFR2-Positive Brain Metastases Introduction In the treatment of breast cancer, tumors that are human epidermal growth factor receptor 2 (HER2) positive exhibit more aggressive characteristics, posing significant challenges for clinical treatment. Since the approval of trastuzumab ...