GPR56-mediated sensing of the steroid hormone 17α-hydroxypregnenolone protects against ferroptosis-induced liver injury

The Role of Protein-Coupled Receptor GPR56 and Its Protective Mechanism in Ferroptosis-Induced Liver Injury In recent years, ferroptosis has emerged as a new form of programmed cell death, becoming a hot topic in scientific research. It is characterized by cell death due to phospholipid peroxidation and is significantly different from traditional a...

CD36 Prevents White Matter Injury by Modulating Microglial Polarization through the TRAF5-MAPK Signal Pathway

CD36 Prevents White Matter Injury by Modulating Microglial Polarization through the TRAF5-MAPK Signal Pathway

Through the Regulation of the TRAF5-MAPK Signaling Pathway in Microglial Polarization, CD36 Inhibits and Alleviates White Matter Damage After Traumatic Brain Injury Research Background Traumatic brain injury (TBI) not only damages gray matter but also causes severe white matter damage. White matter damage results in a significant loss of oligodendr...