Ventilation Practices in Acute Brain Injured Patients and Association with Outcomes: The Ventibrain Multicenter Observational Study

Medicine, Neurology,
mechanical ventilation   acute brain injury   traumatic brain injury   cerebrovascular disease   outcome  

Academic Report on “Ventilation Practices in Acute Brain Injured Patients and Association with Outcomes: The Ventibrain Multicenter Observational Study” Academic Background Mechanical ventilation (MV) is a fundamental component of the intensive care unit (ICU) management of acute brain injury (ABI) patients. However, strong evidence on the best ven...

Relationship Between Structural and Functional Network Connectivity Changes for Patients with Traumatic Brain Injury and Chronic Health Symptoms

Medicine, Neurology, Medical Imaging,
traumatic brain injury   structural connectivity   functional connectivity   chronic symptoms   brain networks   neuroimaging   biomarkers  

Study on Structural and Functional Network Connectivity Changes in Patients with Traumatic Brain Injury Background Introduction Traumatic Brain Injury (TBI) is a common neurological disorder that can lead to long-term cognitive, emotional, and physical symptoms. Although many patients experience symptom relief within months after the injury, a sign...

Lumped Parameter Simulations of Cervical Lymphatic Vessels: Dynamics of Murine Cerebrospinal Fluid Efflux from the Skull

Physics, Fluid Physics, Engineering, Mechanical Engineering, Medicine, Neurology,
cervical lymphatic vessels   lymphatic system   cerebrospinal fluid   traumatic brain injury   numerical simulation   fluid dynamics   intracranial pressure  

Numerical Simulation Study of Cerebrospinal Fluid Drainage through Cervical Lymphatic Vessels Background Introduction Cerebrospinal fluid (CSF) is a clear fluid that circulates around the brain and spinal cord, providing physical protection, nutrient supply, and waste clearance for the central nervous system. In recent years, growing evidence sugge...

Prehospital Lactate Levels Obtained in the Ambulance and Prediction of 2-Day In-Hospital Mortality in Patients with Traumatic Brain Injury

Medicine, Emergency Medicine, Medical Laboratory Science, Neurology, Medical Imaging,
prehospital lactate levels   traumatic brain injury   in-hospital mortality   Glasgow Coma Scale   emergency care  

Research Report Background Overview Traumatic Brain Injury (TBI) is one of the leading causes of permanent disability and death worldwide. These disorders are dynamic and evolving, involving progressive brain injury and pathophysiological changes accompanied by multi-system damage. The severity of TBI is typically assessed using the Glasgow Coma Sc...

CD36 Prevents White Matter Injury by Modulating Microglial Polarization through the TRAF5-MAPK Signal Pathway

CD36 Prevents White Matter Injury by Modulating Microglial Polarization through the TRAF5-MAPK Signal Pathway

Medicine, Neurology, Life Sciences, Cell Biology, Biochemistry, Immunology,
traumatic brain injury   white matter injury   CD36   microglial polarization  

Through the Regulation of the TRAF5-MAPK Signaling Pathway in Microglial Polarization, CD36 Inhibits and Alleviates White Matter Damage After Traumatic Brain Injury Research Background Traumatic brain injury (TBI) not only damages gray matter but also causes severe white matter damage. White matter damage results in a significant loss of oligodendr...

Neuritogenic Glycosaminoglycan Hydrogels Promote Functional Recovery After Severe Traumatic Brain Injury

Chemistry, Polymer Chemistry, Medicinal Chemistry, Materials Science, Organic Polymeric Materials, Medicine, Neurology, Life Sciences, Bioengineering,
neuritogenic   glycosaminoglycan   hydrogel   traumatic brain injury   functional recovery   cell adhesion   neurons  

Neuritogenic Glycosaminoglycan Hydrogels Promote Functional Recovery After Severe Traumatic Brain Injury Traumatic brain injury (TBI) is a serious neurological disorder, and the complexity of its treatment has long plagued the medical community. TBI not only leads to immediate loss of neurological function in patients, but also causes long-term tis...