Human MAIT Cell Response Profiles Biased Toward IL-17 or IL-10 Are Distinct Effector States Directed by the Cytokine Milieu

Life Sciences, Cell Biology, Immunology,
MAIT cells   cytokines   IL-10   IL-17   immune function  

Functional Plasticity of Human MAIT Cells and Their Role in Immune Regulation Academic Background Mucosal-Associated Invariant T cells (MAIT cells) are a type of unconventional T lymphocyte found abundantly in healthy humans, especially in mucosal tissues. MAIT cells exhibit innate-like characteristics, rapidly recognizing antigens derived from mic...

Sex dimorphism in pain threshold and neuroinflammatory response: the protective effect of female sexual hormones on behavior and seizures in an allergic rhinitis model

Medicine, Rheumatology and Immunology, Neurology, Life Sciences, Immunology,
neuroinflammation   sex dimorphism   DNMT1   IL-17   pain   behavior  

Research Report: The Protective Role of Gender on Pain Threshold and Neuroinflammatory Response in Allergic Rhinitis Model Background Introduction Allergic rhinitis (AR) is an inflammation of the nasal mucosa caused by allergens, affecting approximately 40% of the global population. Rhinitis not only causes physical discomfort but is also often acc...