Prognostic Value of the CONUT Score with Immune Checkpoint Inhibitors as First-Line Therapy for Metastatic Malignant Melanoma

Medicine, Oncology, Life Sciences, Immunology,
Immune checkpoint inhibitors   Nutritional status   Melanoma   Prognostic marker   Inflammation  

Prognostic Value of the CONUT Score in Immune Checkpoint Inhibitor Therapy for Metastatic Malignant Melanoma Academic Background The incidence of malignant melanoma (MM) is increasing annually, with approximately 20% of patients progressing to advanced or metastatic melanoma. Immune checkpoint inhibitors (ICIs) have significantly transformed the tr...

Age-dependent Loss of Hapln1 Erodes Vascular Integrity via Indirect Upregulation of Endothelial ICAM1 in Melanoma

Medicine, Medical Laboratory Science, Geriatrics, Oncology, Cardiovascular System, Life Sciences, Cell Biology, Biochemistry, Immunology,
Hapln1   Melanoma   Vascular Integrity   ICAM1   Aging   Extracellular Matrix  

Age-dependent loss of HAPLN1 erodes vascular integrity via indirect upregulation of endothelial ICAM1 in melanoma In a research article titled “Age-dependent loss of HAPLN1 erodes vascular integrity via indirect upregulation of endothelial ICAM1 in melanoma” published in Nature Aging in March 2024, significant findings have been revealed. The study...