Failure in a Population: Tauopathy Disrupts Homeostatic Set-Points in Emergent Dynamics Despite Stability in the Constituent Neurons

Medicine, Neurology, Life Sciences, Cell Biology, Biochemistry,
Tauopathy   Homeostatic Regulation   Neuronal Dynamics   Neurodegenerative Disease   Network Dynamics  

Disturbance of Neuronal Homeostasis and Disruption of Neuronal Network Dynamics Caused by Tau Proteinopathy Background and Research Objectives Homeostatic mechanisms play a crucial role in maintaining the stability of brain functions. Under normal circumstances, neuronal activity set-points, such as firing rates, are dynamically adjusted through ho...

Clinicopathologic and Neuroimaging Correlations of Nonverbal Oral Apraxia in Patients with Neurodegenerative Disease

Medicine, Basic Medical Sciences, Neurology, Medical Imaging,
Nonverbal Oral Apraxia   Neurodegenerative Disease   Clinicopathologic   Neuroimaging   Progressive Supranuclear Palsy   Corticobasal Degeneration  

Nonverbal Oral Apraxia in Patients with Neurodegenerative Diseases: Clinical-Pathological and Neuroimaging Correlations Research Background Nonverbal Oral Apraxia (NVOA) is a condition characterized by the inability to plan, sequence, and execute voluntary oral-facial movements without muscle weakness. NVOA was first identified in stroke patients, ...

Topological Organization of the Brain Network in Patients with Primary Angle-Closure Glaucoma through Graph Theory Analysis

Topological Organization of the Brain Network in Patients with Primary Angle-Closure Glaucoma through Graph Theory Analysis

Medicine, Neurology, Ophthalmology, Medical Imaging, Life Sciences, Biophysics,
Primary Angle-Closure Glaucoma   Functional Magnetic Resonance Imaging   Graph Theory Analysis   Functional Brain Network   Neurodegenerative Disease  

Graph Theory Analysis of Brain Network Topology Structure in Patients with Primary Angle-Closure Glaucoma Research Background Glaucoma is a global blinding eye disease characterized by optic nerve damage and elevated intraocular pressure (IOP) (Kang and Tanna 2021). Among various types of glaucoma, Primary Angle-Closure Glaucoma (PACG) is particula...