Clinicopathologic and Neuroimaging Correlations of Nonverbal Oral Apraxia in Patients with Neurodegenerative Disease

Nonverbal Oral Apraxia in Patients with Neurodegenerative Diseases: Clinical-Pathological and Neuroimaging Correlations Research Background Nonverbal Oral Apraxia (NVOA) is a condition characterized by the inability to plan, sequence, and execute voluntary oral-facial movements without muscle weakness. NVOA was first identified in stroke patients, ...

Graded Multidimensional Clinical and Radiologic Variation in Patients with Alzheimer Disease and Posterior Cortical Atrophy

Research Report on Progressive Multidimensional Clinical and Radiological Variations in Patients with Alzheimer’s Disease and Posterior Cortical Atrophy Background Introduction Alzheimer’s Disease (AD) has multiple phenotypes, including the typical amnestic and non-amnestic (atypical) phenotypes. Posterior Cortical Atrophy (PCA) is a prominent atyp...

Evoked Component Analysis (ECA): Decomposing the Functional Ultrasound Signal with GLM-Regularization

Evoked Component Analysis (ECA): Decomposing Functional Ultrasound Signals Based on GLM Regularization Background The analysis of functional neuroimaging data aims to uncover spatial and temporal patterns of brain activity. Existing data analysis methods mainly fall into two categories: fully data-driven analysis methods and methods that rely on pr...