Development of a Novel Label-Free Functional, Molecular, and Structural Imaging System Combining Optical Coherence Tomography and Raman Spectroscopy for In Vivo Measurement of Rat Retina

Development of a Novel Label-Free Functional, Molecular, and Structural Imaging System Combining Optical Coherence Tomography and Raman Spectroscopy for In Vivo Measurement of Rat Retina

A Revolution in Optical Imaging: Development of a Multimodal Retinal Imaging System Combining OCT and Raman Spectroscopy Research Background and Significance Accessing molecular information of retinal tissue is pivotal for the early diagnosis of ophthalmic and neurodegenerative diseases. However, the current gold standard in retinal imaging—Optical...

Raman-Based Machine Learning Platform Reveals Unique Metabolic Differences Between IDHmut and IDHwt Glioma

Study on Metabolic Differences between IDH Mutant and Wild-type Glioma Cells Using Raman Spectroscopy and Machine Learning Platform Background Introduction In the diagnosis and treatment of gliomas, formalin-fixed, paraffin-embedded (FFPE) tissue sections are commonly used. However, due to background noise interference from the embedding medium, th...