The Effect of B7H6 Ligand on T Cell Responses

Medicine, Infectious Diseases, Rheumatology and Immunology, Oncology, Life Sciences, Immunology,
B7H6   T cells   immune surveillance   NK cells   cancer immunology   antitumor response  

Immunoglobulin Superfamily Ligand B7H6 Enables T Cell Responses under NK Cell Surveillance Background In the field of immunology, understanding the mechanisms regulating T cell immunity is crucial for developing effective therapies for diseases related to T cell dysfunction, such as autoimmune diseases, chronic infections, and cancer. T cells media...

Intratumoral Antigen Signaling Traps CD8+ T Cells to Confine Exhaustion to the Tumor Site

Medicine, Rheumatology and Immunology, Oncology, Life Sciences, Immunology,
cancer immunology   CD8+ T cells   antigen signaling   clonal expansion   T cell exhaustion  

Tumor Immunology Research: The Exhausted State of CD8+ T Cells in Tumors In recent years, immunotherapy has achieved significant progress in the field of tumor treatment. However, tracking the behavior of lymphocytes following antigen signals remains challenging. This study aims to address this issue by developing Antigen Receptor Signaling Reporte...