A Time-Scheduled Oxygen Modulation System Facilitates Bone Regeneration by Powering Periosteal Stem Cells

Academic Background During tissue repair, chronic hypoxia negatively impacts the functionality of stem cells. Periosteal Stem Cells (PSCs), as the primary contributors to bone repair, exhibit unclear behavior under hypoxic conditions. While hypoxia may be beneficial for certain stem cells in the early stages of tissue repair, prolonged hypoxia can ...

Incorporating Bone-Derived ECM into Macroporous Microribbon Scaffolds to Accelerate Bone Regeneration

Incorporating Bone-Derived Extracellular Matrix (Bone-Derived ECM) into Macroporous Microribbon Scaffolds Accelerates Bone Regeneration Research Report With the continuous progress in the biomedical field, the application of tissue engineering and regenerative medicine in various tissue repairs has become increasingly important. However, research o...

Concurrently Bioprinted Scaffolds with Autologous Bone and Allogeneic BMSCs Promote Bone Regeneration through Native BMSC Recruitment

Research on 3D Bioprinted Scaffolds Promoting Bone Regeneration Academic Background In recent years, the incidence of head and craniofacial injuries has significantly increased due to the development of industries and transportation, as well as the frequent occurrence of wars and conflicts. These injuries and related treatments (such as decompressi...