Incorporating Bone-Derived Extracellular Matrix (Bone-Derived ECM) into Macroporous Microribbon Scaffolds Accelerates Bone Regeneration Research Report With the continuous progress in the biomedical field, the application of tissue engineering and regenerative medicine in various tissue repairs has become increasingly important. However, research o...

The Biological Basis of Regional ECM Breakdown and Nerve Invasion in Pancreatic Cancer Background Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most aggressive types of cancer, typically associated with a highly fibrotic stroma, which can account for about 90% of the tumor mass. Although morphological heterogeneity is not addressed in routi...

Physical Immunoevasion: Attenuated Mechanical Communication Facilitates Metastatic Colorectal Cancer Cells to Evade Macrophage Attack Background Introduction Cancer metastasis is a complex and daunting challenge, with metastatic cancer cells capable of evading immune cell attacks, breaching the extracellular matrix (ECM), and migrating to other sit...