Amyloid-Associated Hyperconnectivity Drives Tau Spread Across Connected Brain Regions in Alzheimer’s Disease

Medicine, Neurology,
Alzheimer's disease   tau spread   amyloid   neuronal hyperconnectivity   brain regions   neurodegeneration   functional connectivity  

Amyloid-Associated Hyperconnectivity Drives Tau Spread in Alzheimer’s Disease Academic Background Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques and the abnormal aggregation and spread of tau protein in the brain. The traditional “amyloid cascade hypothesis” posits that...

Intracranial EEG signals disentangle multi-areal neural dynamics of vicarious pain perception

Intracranial EEG signals disentangle multi-areal neural dynamics of vicarious pain perception

Medicine, Neurology, Neurosurgery, Medical Imaging,
Intracranial EEG   Vicarious pain   Neural dynamics   brain regions   empathy  

Research Background and Objectives Empathy is the ability to understand and share the feelings of others and is a crucial foundation for human social interaction and prosocial behavior. Current neuroimaging studies have identified specific brain regions that play key roles in empathetic pain, including the anterior insula (AI), anterior cingulate c...

Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions

Medicine, Neurology, Life Sciences, Biophysics, Humanities and Others,
intracranial EEG   evidence accumulation   perceptual decision   brain regions   neural activity   electrophysiological monitoring   motor-independent  

Academic News Report: Revealing Effector-Independent Evidence Accumulation Dynamics from Intracranial Electrophysiological Recordings Research Background The neural mechanisms underlying the decision-making process have long been a significant topic in neuroscience. Previous studies have indicated that it is possible to identify neural signals rela...