Computational Insights into CRISP3 Downregulation in Cervical Cancer and Its Cervical Lineages Pattern

Medicine, Obstetrics and Gynecology, Oncology,
cervical cancer   CRISP3   biomarkers   prognosis   epigenetic treatment  

Cervical Cancer (CC) is the fourth most common malignant tumor among women worldwide, particularly in low- and middle-income countries, where its incidence and mortality rates remain high. According to statistics, there were over 600,000 new cases and more than 340,000 deaths globally in 2020. The primary cause of cervical cancer is the persistent ...

Exploring Cervical Adenocarcinoma: Epidemiological Insights, Diagnostic and Therapeutic Challenges, and Pathogenetic Mechanisms

Medicine, Obstetrics and Gynecology, Oncology,
cervical adenocarcinoma   cervical cancer   gynecological oncology   organoid   single-cell RNA sequencing   tumor microenvironment  

Exploring Cervical Adenocarcinoma: Epidemiology, Diagnostic and Therapeutic Challenges, and Pathogenetic Mechanisms Academic Background Cervical cancer poses a significant threat to women’s health globally, particularly in developing countries. The main histological types of cervical cancer include squamous cell carcinoma (SCC) and cervical adenoca...

Silencing of STEAP3 Suppresses Cervical Cancer Cell Proliferation and Migration via JAK/STAT3 Signaling Pathway

Medicine, Oncology,
STEAP3   cervical cancer   JAK/STAT3 signaling pathway   cell proliferation   cell migration   DNA methylation   iron metabolism  

The Role and Mechanism of STEAP3 in Cervical Cancer Background Cervical cancer (CC) is the fourth most common cancer among women globally, with approximately 600,000 new cases and 300,000 deaths annually. Although the five-year survival rate for early-stage cervical cancer patients exceeds 85% through treatments such as surgery, radiotherapy, and c...