Colorectal Cancer (CRC) is one of the most prevalent malignancies globally, with its prognosis closely related to immune responses within the tumor microenvironment. In recent years, Tertiary Lymphoid Structures (TLS), as an essential component of the tumor microenvironment, have been associated with favorable patient outcomes. TLS are aggregates o...

Cervical Cancer (CC) is the fourth most common malignant tumor among women worldwide, particularly in low- and middle-income countries, where its incidence and mortality rates remain high. According to statistics, there were over 600,000 new cases and more than 340,000 deaths globally in 2020. The primary cause of cervical cancer is the persistent ...

Background Introduction Glioma is one of the most common primary tumors of the central nervous system, and its prognosis and treatment methods vary significantly depending on molecular characteristics. In recent years, with the advancement of molecular pathology, IDH (isocitrate dehydrogenase) mutations have been identified as important molecular m...

A Transformer Model Integrating PET Imaging and Clinical Data: A Multicenter Digital Biopsy Study for Predicting Pathological Grading and Prognosis of Follicular Lymphoma Academic Background Follicular Lymphoma (FL) is the most common indolent Non-Hodgkin Lymphoma in Western countries, accounting for approximately 30% of newly diagnosed cases. Acco...

Utilizing Bifurcated Allogeneic Vein Grafts to Prevent Sinistral Portal Hypertension Following Pancreaticoduodenectomy Academic Background Pancreatic cancer is a highly malignant tumor with a poor prognosis, with a 5-year survival rate of less than 10%. The early invasive growth of pancreatic cancer often involves the portal vein system, particular...

Comparative Study on Treatment Strategies for Esophageal Cancer Academic Background Esophageal cancer is one of the digestive system tumors with high incidence and mortality rates worldwide, particularly in Asia, where the incidence of esophageal squamous cell carcinoma (SCC) is notably prominent. Although significant progress has been made in the ...

Evaluation of Treatment Outcomes Using DNLR and GNRI in Combination Therapy for Hepatocellular Carcinoma Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide, particularly in Asia. Due to its lack of early symptoms, many patients are diagnosed at an advanced stage, making surgical resection unfeasible. In r...

Clinical Analysis of MOG Antibody-Associated Disease Overlapping with Anti-NMDAR Encephalitis Background In recent years, with the in-depth study of autoimmune encephalitis (AE) and demyelinating diseases of the central nervous system (CNS), scientists have identified some rare cases of overlapping syndromes. Among them, the overlap between MOG Ant...

Review of the Impact of FISH-Detected Cytogenetic Abnormalities on Prognosis in AL Amyloidosis in the Era of Daratumumab Therapy Background Immunoglobulin light chain (AL) amyloidosis is a rare disease characterized by organ dysfunction caused by the deposition of light chain proteins secreted by abnormal plasma cells. However, the heterogeneous cl...

Progress in Molecular Classification of Follicular Lymphoma: A Dual Typing Predictive Model Based on RNA Sequencing and Immunohistochemistry Follicular Lymphoma (FL) is a B-cell malignancy characterized by a slow clinical progression, with a median overall survival extending up to 20 years. However, the heterogeneous nature of FL leads to significa...