Pallidal Spike-Train Variability and Randomness are the Most Important Signatures to Classify Parkinson's Disease and Cervical Dystonia

Medicine, Neurology, Life Sciences,
Parkinson's disease   cervical dystonia   globus pallidus   spike-train variability   randomness   deep brain stimulation   neuronal activity  

Classification Study of Parkinson’s Disease and Cervical Dystonia Academic Background Parkinson’s Disease (PD) and Cervical Dystonia (CD) are two common movement disorders whose pathological mechanisms are closely related to abnormal neuronal activity in the basal ganglia. The basal ganglia are a crucial brain structure for motor control, with the ...

Periodic and Aperiodic Components of Subthalamic Nucleus Activity Reflect Different Aspects of Motor Impairment in Parkinson's Disease

Medicine, Neurology,
Parkinson's disease   subthalamic nucleus   motor impairment   periodic activity   aperiodic activity   deep brain stimulation   levodopa  

Periodic and Aperiodic Components of Subthalamic Nucleus Activity Reflect Different Aspects of Motor Impairment in Parkinson’s Disease Background Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by core symptoms such as bradykinesia, rigidity, and tremor. Although the neurophysiology of PD has been extensively studied, ...

Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients

Medicine, Basic Medical Sciences, Neurology, Neurosurgery, Life Sciences, Biophysics,
essential tremor   cerebellum   olivary body   neuronal population activity   EEG   frequency encoding   deep brain stimulation  

Encoding of Cerebellar-Olivary Neuronal Ensemble Activity for Tremor Frequency in Mice and Patients with Essential Tremor Research Background Essential Tremor (ET) is a common movement disorder characterized primarily by action tremor, affecting about 20% of the elderly population. The frequency and intensity of tremor are core features of ET. Howe...