Distinguishing Parkinsonian Rest Tremor from Voluntary Hand Movements through Subthalamic and Cortical Activity

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized mainly by resting tremor, bradykinesia, and rigidity. Deep Brain Stimulation (DBS) has been widely used to treat the motor symptoms of PD (Krauss et al., 2021). However, DBS treatment also has significant side effects, most of which are caused by the extension of stimulat...

Neurophysiological Features of STN LFP Underlying Sleep Fragmentation in Parkinson's Disease

Neurophysiological Features of STN LFP Underlying Sleep Fragmentation in Parkinson's Disease

Parkinson’s Disease (PD) is a neurodegenerative disease primarily characterized by dopaminergic neuron damage. Aside from causing motor disorders, over 80% of Parkinson’s disease patients also suffer from sleep disorders. Fragmented sleep is a common type of sleep disturbance among PD patients. It is associated not only with sleep maintenance insom...