Collecting Duct NCOR1 Controls Blood Pressure by Regulating Mineralocorticoid Receptor

Medicine, Endocrinology, Nephrology, Cardiovascular System, Life Sciences, Biochemistry,
hypertension   collecting duct   NCOR1   ENaC   mineralocorticoid receptor   sodium reabsorption   blood pressure regulation  

Collecting Duct NCOR1 Regulates Blood Pressure by Controlling Mineralocorticoid Receptor Academic Background Hypertension is one of the major risk factors for cardiovascular and cerebrovascular diseases globally, with complex and not fully elucidated mechanisms. The kidney plays a critical role in blood pressure regulation, particularly in the proc...

Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1

Medicine, Infectious Diseases, Cardiovascular System, Life Sciences, Microbiology,
Klebsiella pneumoniae   extracellular vesicles   endothelial dysfunction   endothelial senescence   SIRT1   hypertension   inflammatory response  

Klebsiella pneumoniae-Derived Extracellular Vesicles Impair Endothelial Function by Inhibiting SIRT1 Academic Background Hypertension is a global health issue with a complex pathogenesis involving multiple factors. In recent years, the role of gut microbiota in hypertension has garnered significant attention. Studies have shown that dysbiosis of th...