ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis

Medicine, Hematology, Oncology, Life Sciences, Cell Biology, Biochemistry, Genetics,
ARID1A   SWI/SNF   transcription factors   memory B cells   lymphoma   chromatin remodeling   cancer  

ARID1A Loss and B Cell Fate and Lymphoma Occurrence Background Introduction This paper investigates the critical role of ARID1A (AT-Rich Interactive Domain 1A) in B cell fate determination and lymphoma occurrence. ARID1A is an important subunit of the BRG1/Brahma-associated factors (BAF) complex, with mutations commonly found in various human malig...