A Two-Phase Epigenome-Wide Four-Way Gene–Smoking Interaction Study of Overall Survival for Early-Stage Non-Small Cell Lung Cancer

Medicine, Respiratory System, Oncology,
epigenomics   four-way interaction   gene–smoking interaction   non-small cell lung cancer   survival analysis   DNA methylation   molecular mechanisms  

Study on the Four-Way Gene-Smoking Interaction and Survival in Early-Stage Non-Small Cell Lung Cancer Research Background Lung cancer is one of the most prevalent malignancies worldwide and a leading cause of cancer-related mortality. According to global cancer statistics, approximately 2.5 million new cases are diagnosed annually, with 1.8 million...