Effectiveness of Bundle of Care on Tolerance of Awake-Prone Positioning in Patients with Acute Respiratory Failure: A Multicenter Observational Study

Effectiveness Study of Awake Prone Positioning Care Strategies in Patients with COVID-19 Related Acute Respiratory Failure Background Introduction During the COVID-19 pandemic, acute respiratory failure (Acute Respiratory Failure, ARF) became one of the main complications in critically ill patients. For patients requiring high-flow nasal oxygen (Hi...

Multisite DNA Methylation Alterations of Peripheral Blood Mononuclear Cells Serve as Novel Biomarkers for the Diagnosis of AIS/Stage I Lung Adenocarcinoma: A Multicenter Cohort Study

Novel Early Diagnosis Method for Lung Adenocarcinoma Based on DNA Methylation in Peripheral Blood Mononuclear Cells Background Lung adenocarcinoma (LUAD) is one of the leading causes of cancer-related deaths worldwide, accounting for approximately 40% of lung cancer cases. Despite significant advancements in treatment, the prognosis of LUAD remains...

Hepatic Arterial Infusion Chemotherapy-Based Conversion Hepatectomy in Responders Versus Nonresponders with Hepatocellular Carcinoma: A Multicenter Cohort Study

Hepatic Arterial Infusion Chemotherapy (HAIC)-Based Conversion Hepatectomy in Patients with Hepatocellular Carcinoma Academic Background Hepatocellular carcinoma (HCC) is one of the most common liver malignancies worldwide, particularly in China, where its incidence and mortality rates remain high. Despite advancements in treatment strategies, radi...

Reliability of Central Vein Sign Imaging with 3T FLAIR* in a Multicenter Study

Reliability of Central Vein Sign Imaging with 3T FLAIR* in a Multicenter Study Academic Background Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by the formation of white matter lesions (WMLs). Magnetic Resonance Imaging (MRI) is a crucial tool for diagnosing and monitoring MS, particularly T2...