Single-Molecule Dynamic Structural Biology: Breakthrough in Observing DNA-Protein Interactions Using Graphene Background Introduction The intricate and precise interactions between DNA and proteins play a crucial role in fundamental biological functions such as DNA replication, transcription, and repair. However, observing these interaction process...

The Critical Role of Kindlin-3 in β2 Integrin Clustering Academic Background Neutrophils are the most abundant type of white blood cells in human blood, and their recruitment is essential for innate immunity and inflammatory responses. The initial and critical step in neutrophil recruitment is their adhesion to vascular endothelial cells, which dep...

MINFLUX Nanoscopy in Biological Tissue: Breaking the Resolution Barrier of Fluorescence Microscopy Academic Background Fluorescence microscopy plays a crucial role in biological research, but its resolution is limited by the diffraction barrier, typically around 200 nanometers. In recent years, the development of super-resolution microscopy (SR) te...