A New Protein Regulating Mitochondrial Function for Maintaining Hematopoietic Stem Cell Viability: The Role of Nynrin

A New Protein Regulating Mitochondrial Function for Maintaining Hematopoietic Stem Cell Viability: The Role of Nynrin

Nynrin Protects Hematopoietic Stem Cell Function by Inhibiting Mitochondrial Permeability Transition Pore Opening Background and Research Motivation Hematopoietic stem cells (HSCs) are core cells that maintain the function of the hematopoietic system, showing unique adaptability to stress environments such as radiation damage. However, while conven...

Aging-Induced MCPH1 Translocation Activates Necroptosis and Impairs Hematopoietic Stem Cell Function

Study on MCPH1 Nuclear Transfer Induced by Aging Activating Necrosis and Impairing Hematopoietic Stem Cell Function Research Background The aging of hematopoietic stem cells is associated with an increased risk of various blood diseases, and DNA damage is a significant factor driving the aging of hematopoietic stem cells. However, the underlying mo...