Intestinal Epithelium–Derived IL-34 Reprograms Macrophages to Mitigate Gastrointestinal Tract Graft-Versus-Host Disease

Medicine, Rheumatology and Immunology, Basic Medical Sciences, Gastroenterology, Hematology, Life Sciences, Cell Biology, Immunology,
Graft-versus-host disease   Macrophages   IL-34   Intestinal epithelium   Immunomodulation  

Academic Report on the Role of Intestinal Epithelium-Derived IL-34 in Alleviating Graft-versus-Host Disease 1. Academic Background Graft-versus-Host Disease (GVHD) is a severe complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT), and gastrointestinal (GI) GVHD is the primary determinant of morbidity and mortality du...