Retrieval of Conditioned Immune Response in Male Mice is Mediated by an Anterior–Posterior Insula Circuit

Medicine, Neurology, Life Sciences, Cell Biology, Immunology,
Conditioned Immune Response   Insula Circuit   Male Mice   Immunomodulation   Pavlovian Conditioning  

Retrieval of Conditioned Immune Response in Mice is Mediated by an Anterior-Posterior Insular Circuit Academic Background The bidirectional relationship between the brain and the immune system is a cornerstone of philosophical and scientific research. In recent years, researchers have identified multiple pathways through which the immune system inf...

Intestinal Epithelium–Derived IL-34 Reprograms Macrophages to Mitigate Gastrointestinal Tract Graft-Versus-Host Disease

Medicine, Rheumatology and Immunology, Basic Medical Sciences, Gastroenterology, Hematology, Life Sciences, Cell Biology, Immunology,
Graft-versus-host disease   Macrophages   IL-34   Intestinal epithelium   Immunomodulation  

Academic Report on the Role of Intestinal Epithelium-Derived IL-34 in Alleviating Graft-versus-Host Disease 1. Academic Background Graft-versus-Host Disease (GVHD) is a severe complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT), and gastrointestinal (GI) GVHD is the primary determinant of morbidity and mortality du...

Therapeutic Potential of 2-Bromo-1,4-Naphthoquinone in Multiple Sclerosis

Medicine, Rheumatology and Immunology, Neurology, Life Sciences, Biochemistry, Immunology,
Multiple Sclerosis   2-Bromo-1,4-Naphthoquinone   Immunomodulation   Central Nervous System   Autoimmune Disease  

2-Bromo-1,4-naphthoquinone Promotes CD8+ T Cell Expansion and Limits Th1/Th17 Cell Development to Alleviate Experimental Autoimmune Encephalomyelitis Introduction Multiple Sclerosis (MS) is a chronic autoimmune disease that primarily affects the Central Nervous System (CNS), impacting approximately 3 million people worldwide. The onset of MS is ass...