Distinct Palmitoylation of FoxP3 Regulates the Function of Regulatory T Cells via Palmitoyltransferases

Unique Foxp3 Palmitoylation Regulates Tregs Function through Palmitoyltransferases Regulatory T cells (Tregs) play a crucial role in maintaining immune homeostasis and preventing excessive immune responses. As important suppressors of immune reactions, Tregs help maintain immune tolerance, thereby preventing autoimmune diseases. However, in the tum...

The Therapeutic Role of Interferon-γ in Experimental Autoimmune Encephalomyelitis is Mediated Through a Tolerogenic Subset of Splenic CD11b+ Myeloid Cells

The Therapeutic Role of IFN-γ in Experimental Autoimmune Encephalomyelitis is Mediated by Tolerogenic Subsets of Splenic CD11b+ Myeloid Cells Research Background Multiple sclerosis (MS) is a chronic autoimmune disease characterized by demyelination and axonal damage in the central nervous system (CNS). Although the etiology of MS is unclear, both g...