Targeting STING in Dendritic Cells Alleviates Psoriatic Inflammation Psoriasis is a common chronic inflammatory skin disease primarily caused by abnormal activation of dendritic cells (DCs) and T cells, ultimately leading to increased cytokines such as interleukin (IL)-23 and IL-17A. The cGAS-STING pathway is known to play a key role in psoriatic i...

The Key Role of Retina Microglia in Pathological Angiogenesis and the Immunotherapeutic Potential of the cGAS-STING Pathway Background Pathological angiogenesis is common in various neovascular ophthalmic diseases, such as Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD) [1]. During these diseases, bone marrow cells, including r...