Breaking Boundaries: Role of the Brain Barriers in Metastatic Process

The Role of Brain Barriers in Brain Metastasis Background Introduction Brain metastases (BMs) are the most common intracranial tumors in adults, occurring 3 to 10 times more frequently than primary brain tumors. Despite multimodal treatments including surgical resection, radiotherapy, and chemotherapy, the prognosis for brain metastases remains poo...

MERTK Reduces Blood-Spinal Cord Barrier Permeability Through the RhoA/ROCK1/P-MLC Pathway After Spinal Cord Injury

Study on MERTK Reducing Blood-Spinal Cord Barrier Permeability after Spinal Cord Injury via RhoA/ROCK1/p-MLC Pathway Spinal Cord Injury (SCI) is a central nervous system disease caused by trauma, inflammation, tumors, or other pathological reasons, resulting in sensory, motor, and autonomic nervous system dysfunction in patients, imposing a heavy b...