The Discharge Characteristics of Motor Units Innervating Functionally Paralyzed Muscles

Study on the Discharge Characteristics of Motor Neurons Innervating Paralyzed Muscles after Spinal Cord Injury Academic Background Spinal Cord Injury (SCI) is a severe neurological injury that typically leads to the loss of motor and sensory functions below the injury level. Although patients clinically diagnosed with complete SCI are considered un...

Photocrosslinkable Human Amniotic Membrane Hydrogel for Recovery from Spinal Cord Injury

Photocrosslinked Human Amniotic Membrane Hydrogel for Spinal Cord Injury Repair Academic Background Spinal Cord Injury (SCI) is a severe neurological disorder that often leads to loss of motor function and a decline in the quality of life for patients. Despite significant advancements in tissue engineering and regenerative medicine in recent years,...

The Discharge Characteristics of Motor Units Innervating Functionally Paralyzed Muscles

Functional Study of Motor Neurons After Spinal Cord Injury Background Introduction Spinal Cord Injury (SCI) is a severe neurological disorder that often leads to the loss of motor function in patients. Although patients may lose voluntary control of limb movements after SCI, studies have shown that motor neurons below the injury level may still ret...

A Glucocorticoid Spike Derails Muscle Repair to Heterotopic Ossification After Spinal Cord Injury

A Glucocorticoid Spike Derails Muscle Repair to Heterotopic Ossification After Spinal Cord Injury

Academic Background and Problem Statement Neurogenic Heterotopic Ossification (NHO) is a pathological condition where ectopic bone tissue forms in muscles following severe central nervous system (CNS) injuries, such as spinal cord injury (SCI), traumatic brain injury (TBI), or stroke. NHO not only impairs motor function but can also lead to joint s...

MERTK Reduces Blood-Spinal Cord Barrier Permeability Through the RhoA/ROCK1/P-MLC Pathway After Spinal Cord Injury

Study on MERTK Reducing Blood-Spinal Cord Barrier Permeability after Spinal Cord Injury via RhoA/ROCK1/p-MLC Pathway Spinal Cord Injury (SCI) is a central nervous system disease caused by trauma, inflammation, tumors, or other pathological reasons, resulting in sensory, motor, and autonomic nervous system dysfunction in patients, imposing a heavy b...

Ferroptosis Inhibitor Improves Outcome After Early and Delayed Treatment in Mild Spinal Cord Injury

Ferroptosis Inhibitors Improve Early and Delayed Treatment Outcomes of Mild Spinal Cord Injury Academic Background Spinal cord injury (SCI) causes significant secondary damage not only in the acute period but also in the chronic period. These injuries are typically triggered by multiple factors, including oxidative stress, inflammatory response, an...