Staphylococcus aureus Vesicles Impair Cutaneous Wound Healing through p38 MAPK-MERTK Cleavage-Mediated Inhibition of Macrophage Efferocytosis

Medicine, Infectious Diseases, Life Sciences, Cell Biology, Immunology, Microbiology,
Staphylococcus aureus   extracellular vesicles   wound healing   efferocytosis   MERTK  

Staphylococcus Aureus Vesicles Impair Cutaneous Wound Healing Through p38 MAPK-MerTK Cleavage-Mediated Inhibition of Macrophage Efferocytosis Background Introduction Staphylococcus aureus (S. aureus) is one of the primary pathogens causing chronic wound infections, particularly in diabetic patients, with an infection rate as high as 65%. One of the...

MERTK Reduces Blood-Spinal Cord Barrier Permeability Through the RhoA/ROCK1/P-MLC Pathway After Spinal Cord Injury

Medicine, Neurosurgery,
spinal cord injury   MERTK   blood-spinal cord barrier   RhoA/ROCK1/P-MLC pathway   apoptosis   inflammation  

Study on MERTK Reducing Blood-Spinal Cord Barrier Permeability after Spinal Cord Injury via RhoA/ROCK1/p-MLC Pathway Spinal Cord Injury (SCI) is a central nervous system disease caused by trauma, inflammation, tumors, or other pathological reasons, resulting in sensory, motor, and autonomic nervous system dysfunction in patients, imposing a heavy b...