The Impact of the Maternal X Chromosome on Cognition and Brain Aging in Female Mice Background Introduction In mammals, female cells possess two X chromosomes, one from the mother (maternal X chromosome, Xm) and one from the father (paternal X chromosome, Xp). During embryonic development, one of the X chromosomes is randomly inactivated, a process...

Spatial Transcriptomic Clocks Reveal Cell Proximity Effects in Brain Aging Academic Background With aging, cognitive function declines, and the risk of neurodegenerative diseases significantly increases. Brain aging is a complex process accompanied by numerous cellular changes. However, how aging cells affect neighboring cells and how this contribu...