The Role of KV7 Channels in Modulating Tension and Calcium Signaling in Mouse Corpus Cavernosum

Study on the Role of KV7 Channels in Regulating Smooth Muscle Contraction in Mouse Corpus Cavernosum Academic Background Erectile dysfunction (ED) is a significant health issue that impacts the quality of life for men. Since the introduction of phosphodiesterase 5 (PDE5) inhibitors like Sildenafil in the 1990s, there has been notable progress in th...

Astrocyte Ensembles Manipulated with Astrolight Tune Cue-Motivated Behavior

New Discoveries in Astrocyte Regulation of Behavior: Application of the AstroLight Tool Academic Background For a long time, neuroscience research has primarily focused on neuronal activity, while neglecting the role of astrocytes in brain function. Although astrocytes are one of the most numerous cell types in the brain, they have traditionally be...

Phosphorylation of BOK at Ser-8 Blocks Its Ability to Suppress IP3R-Mediated Calcium Mobilization

The New Role of BOK Protein in Calcium Signaling Regulation Background Introduction BOK (Bcl-2-related ovarian killer) is a member of the Bcl-2 protein family and has long been thought to play a role in cell apoptosis. However, recent studies suggest that BOK may also have non-apoptotic functions, particularly in the regulation of calcium ion (Ca²⁺...

Layer-Specific Anatomical and Physiological Features of the Retina’s Neurovascular Unit

Academic Report on the Study of Layer-Specific Anatomical and Physiological Characteristics of the Retinal Neurovascular Unit Background and Problem Statement Retinal processing, similar to all neural computations, is metabolically expensive and involves the dynamic regulation of blood flow, known as neurovascular coupling (NVC). The retina is supp...