Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells

Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells

Medicine, Gastroenterology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Microbiology,
circadian rhythm   cancer metastasis   intestinal microbiota   myeloid-derived suppressor cells   tumor microenvironment  

Disruption of Circadian Rhythm Promotes Cancer Metastasis and Myeloid-Derived Suppressor Cell Accumulation Triggered by Intestinal Microbes Academic Background and Research Motivation Cancer metastasis is the leading cause of death for most cancer patients, with colorectal cancer (CRC) drawing significant attention due to its high global incidence ...

Physical Immune Escape: Weakened Mechanical Communication Leads to Escape of Metastatic Colorectal Carcinoma Cells from Macrophages

Physical Immune Escape: Weakened Mechanical Communication Leads to Escape of Metastatic Colorectal Carcinoma Cells from Macrophages

Life Sciences, Cell Biology, Immunology, Biophysics,
mechanical signals   immune escape   extracellular matrix   cancer metastasis   macrophages  

Physical Immunoevasion: Attenuated Mechanical Communication Facilitates Metastatic Colorectal Cancer Cells to Evade Macrophage Attack Background Introduction Cancer metastasis is a complex and daunting challenge, with metastatic cancer cells capable of evading immune cell attacks, breaching the extracellular matrix (ECM), and migrating to other sit...