The Protective Roles of Integrin α4β7 and Amphiregulin-Expressing Innate Lymphoid Cells in Lupus Nephritis

Medicine, Rheumatology and Immunology, Nephrology, Life Sciences, Immunology,
innate lymphoid cells   tissue residency   adhesion molecules   integrins   kidney   lupus nephritis   amphiregulin  

Scientific Research Report: The Protective Role of Integrin α4β7 and Type 2 Innate Lymphoid Cells in Nephritis In a recent study, an international research team led by Dr. Seungwon Ryu revealed the critical protective role of integrin α4β7 and Type 2 Innate Lymphoid Cells (ILC2s) in nephritis caused by Systemic Lupus Erythematosus (SLE). The study ...

Gfi1b Specifies Developmental Potential of Innate Lymphoid Cell Progenitors in the Lungs

Medicine, Rheumatology and Immunology, Respiratory System, Life Sciences, Cell Biology, Immunology, Microbiology,
Gfi1b   lungs   innate lymphoid cells   developmental potential   progenitor cells   immunity  

Background Introduction In respiratory diseases, the lung is a sensitive organ exposed to the external environment, making it susceptible to pathogens, allergens, and toxic particles. Due to the high morbidity and mortality associated with respiratory diseases (such as asthma), it is crucial to study the mechanisms protecting the cells on the surfa...