Neoantigen-Specific mRNA/DC Vaccines for Effective Anticancer Immunotherapy

Medicine, Oncology, Life Sciences, Immunology,
neoantigen   mRNA vaccine   dendritic cells   anticancer immunotherapy   personalized treatment  

Effectiveness of Neoantigen-Specific mRNA/DC Vaccines in Anticancer Immunotherapy Academic Background Cancer immunotherapy has emerged as a significant breakthrough in cancer treatment in recent years. Among the various approaches, dendritic cell (DC) vaccines have shown potential in extending the survival of some advanced cancer patients. However,...

Ongoing Evolution of SARS-CoV-2 Drives Escape from mRNA Vaccine-Induced Humoral Immunity

Medicine, Infectious Diseases, Life Sciences, Immunology, Microbiology,
SARS-CoV-2   mRNA vaccine   humoral immunity   viral mutation   neutralizing antibodies  

The Ongoing Evolution of SARS-CoV-2 Drives Escape from mRNA Vaccine-Induced Humoral Immunity Academic Background Since its emergence in late 2019, SARS-CoV-2 has undergone continuous evolution, giving rise to multiple variants. These variants have enhanced their transmissibility and immune evasion capabilities through mutations, particularly agains...

Dendritic-Cell-Targeting Virus-Like Particles as Potent mRNA Vaccine Carriers

Medicine, Infectious Diseases, Rheumatology and Immunology, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology,
dendritic cells   virus-like particles   mRNA vaccine   SARS-CoV-2   high efficacy  

Dendritic-cell-targeting Virus-like Particles as Potent mRNA Vaccine Carriers Introduction In vaccine development, especially mRNA vaccines, significant achievements have been made in recent years. The mRNA vaccines developed by Moderna and Pfizer/BioNTech against COVID-19 have set a successful precedent, greatly advancing the development of mRNA v...