Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles

Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles

Chemistry, Medicinal Chemistry, Chemical Engineering, Medicine, Oncology, Life Sciences, Biochemistry, Bioengineering, Genetics,
small extracellular vesicles   gene delivery   pH-responsive   graphene quantum dots   lysosomal escape   breast cancer   siRNA  

Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles Academic Background In recent years, small extracellular vesicles (sEVs) have become a hot topic in the field of drug delivery due to their natural origin and inherent homing properties. sEVs are lipid nanoparticles secreted b...

Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

Medicine, Basic Medical Sciences, Geriatrics, Life Sciences, Biochemistry,
young plasma   small extracellular vesicles   mitochondrial energy metabolism   aging   functional decline   proteomics   PGC-1α  

Small Extracellular Vesicles in Young Plasma Reverse Age-Related Functional Decline by Improving Mitochondrial Energy Metabolism Background In recent years, research on heterochronic parabiosis has revealed significant regenerative effects of young blood on elderly tissues. However, the specific regenerative mechanisms are not fully understood. Thi...