Global Profiling of Alternative Splicing in Non-Small Cell Lung Cancer Reveals Novel Histological and Population Differences

Medicine, Oncology, Life Sciences, Biochemistry, Genetics,
non-small cell lung cancer   alternative splicing   population differences   tumor biology   biomarkers   molecular subtypes   therapeutic targets  

Global Profiling of Alternative Splicing in Non-Small Cell Lung Cancer Reveals Novel Histological and Population Differences Academic Background Lung cancer is one of the most frequently diagnosed cancers in the United States, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Among NSCLC, lung adenocarcinoma (LUAD) and l...

A prognostic neural epigenetic signature in high-grade glioma

Medicine, Neurology, Neurosurgery, Oncology, Life Sciences, Cell Biology, Biochemistry,
glioma   neural epigenetics   prognostic signature   tumor biology   neuroscience  

Study of Neuroepithelial Genetic Markers and Prognosis in High-Grade Gliomas Background and Research Motivation High-grade gliomas are highly malignant brain tumors with generally poor patient prognosis. Previous preclinical model studies have suggested that interactions between neural and tumor cells drive tumor growth, but clinical validation of ...