Development of an Orthotopic Medulloblastoma Zebrafish Model for Rapid Drug Testing

Academic Background Medulloblastoma (MB) is one of the most common malignant brain tumors in children. Although recent advances in molecular characterization and multimodal treatment have significantly improved patient survival rates, the prognosis of medulloblastoma remains closely related to molecular subtypes, particularly for patients with Grou...

Lactate Secreted by Glycolytic Conjunctival Melanoma Cells Attracts and Polarizes Macrophages to Drive Angiogenesis in Zebrafish Xenografts

Academic Background Conjunctival Melanoma (COM) is a rare but potentially lethal ocular cancer, particularly when metastasis occurs, with limited treatment options. Although current treatments for primary conjunctival melanoma are relatively effective, once metastasis occurs, patient survival rates drop significantly, with most patients surviving l...