Enhanced Epithelial-Mesenchymal Transition Signatures Are Linked with Adverse Tumor Microenvironment, Angiogenesis, and Worse Survival in Gastric Cancer

Medicine, Gastroenterology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
epithelial-mesenchymal transition   gastric cancer   gene set variation analysis   survival rate   tumor microenvironment   angiogenesis  

Enhanced EMT Characteristics Associated with Unfavorable Tumor Microenvironment, Angiogenesis, and Poorer Prognosis in Gastric Cancer Academic Background Epithelial-Mesenchymal Transition (EMT) is an extremely important mechanism that promotes the metastasis of cancer cells. However, despite its apparent importance, the clinical significance of EMT...

Disturbance in Cerebral Blood Microcirculation and Hypoxic-Ischemic Microenvironment are Associated with the Development of Brain Metastasis

Medicine, Neurology, Neurosurgery, Oncology, Life Sciences, Immunology,
cerebral blood microcirculation   hypoxic-ischemic microenvironment   brain metastasis   angiogenesis   ANG-2   VEGF   anti-angiogenic therapy  

Microcirculatory Disorders of Cerebral Blood Flow and the Hypoxic-Ischemic Microenvironment Related to Brain Metastasis Development Background and Research Motivation Brain metastasis (BM) is an increasing challenge in oncology due to its severe impact on neurological function, limited treatment options, and resulting poor prognosis. BM develops th...