Estrogen Deficiency Alters Vascularization and Mineralization Dynamics: Insight from a Novel 3-D Humanized and Vascularized Bone Organoid Model

The Impact of Estrogen Deficiency on Vascularization and Mineralization Dynamics—Insights from a Novel 3D Humanized and Vascularized Bone Organoid Model Academic Background Osteoporosis is a common bone disease, particularly prevalent among postmenopausal women. Osteoporosis not only manifests as a reduction in bone mass but also involves changes i...

Global 3D Model of Mantle Attenuation Using Seismic Normal Modes

Global 3D Model of Mantle Attenuation: A Study Based on Seismic Normal Modes Academic Background The structure and dynamic processes of Earth’s interior have always been at the core of geoscientific research. Mantle convection is the primary mechanism driving plate tectonics, volcanic eruptions, and earthquakes. However, traditional seismic tomogra...

Wnt/β-catenin Signaling is Critical for the Tumorigenesis of Choroid Plexus Tumors

The Critical Role of Wnt/β-catenin Signaling in Choroid Plexus Tumorigenesis Background Introduction The choroid plexus (CHP) is a secretory epithelial structure located in the brain ventricles, primarily responsible for the secretion of cerebrospinal fluid (CSF) and the establishment of the blood-CSF barrier. Choroid plexus tumors (CPTs) are rare ...